Week 1 (session one) will focus on a) life history theory, b) tradeoffs involving the microbiome affecting obesity and allergy and c) the evolution of aging
Week 3 will consider the microbiome as a trojan horse – what does this mean for the critically ill, surgical patients, and people exposed to heat and other stresses.
Week 4 will be a deep dive into sepsis as pathology versus adaptation to overwhelming infection. Why did Xigris, the only drug ever approved by the FDA specifically for sepsis, ultimately fail to help patients, leading to its removal from the market? Can we harness evolutionary principles to design new treatments for sepsis? (Spoiler: yes we can!)
Emergency Physician, Educator, Researcher, interested in the microbiome, evolution, and medicine