How important is gene-environment mismatch? What is the Paleo diet?

1) Quickly skim this recent piece in the Huffington Post

2) Next read Eaton (2006)-Ancestral human diet

2) Then read this review:

Paleofantasy by Marlene Zuk

Finally, read my post about nutrient signaling on the Evolution & Medicine Review.

If you have time look at the entire paper: Alcock_Franklin_Kuzawa

Writing Assignment:

For Tuesday: Pima Indians (Tohono O’odham) of Arizona have the highest rates of diabetes in the world. They eat processed foods and refined carbohydrates like other Arizonans (the typical American diet).  Their Pima relatives who farm in the Sierrra Madre of Mexico eat a more traditional diet and have much less diabetes and obesity. In light of the Paleo diet hypothesis and the backlash it has generated, how would you explain the differences in diabetes between the two closely related groups

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Joe Alcock

Emergency Physician, Educator, Researcher, interested in the microbiome, evolution, and medicine