Menu Home

Fat Fights Back – the Podcast

Fat, especially visceral fat, has an important immune function, especially in gastrointestinal infections and in response to GI pathogens in the microbiome. In Podcast #39, Coffee Brown and I discuss Mary Jane West Eberhard’s paper on the evolutionary function of fat and a developmental explanation for the obesity epidemic. Her paper lays the groundwork for understanding why some early life experiences make us more likely to have chronic diseases like heart disease, diabetes, and obesity.

Screen Shot 2019-02-28 at 7.36.20 PM.png

The key to obesity lies in the adaptive immune function of fat, and its role in fighting gut infections and containing unhealthy microbiomes

 

Her paper is titled: “Nutrition, the visceral immune system, and the evolutionary origins of pathogenic obesity. Proceedings of the National Academy of Sciences. ” Read the  full text version here: https://doi.org/10.1073/pnas.1809046116

I like the argument. My explanation for obesity is similar and has a microbiome focus. The microbiome explains everything, doesn’t it?

 

Categories: Uncategorized

Joe Alcock

Emergency Physician, Educator, Researcher, interested in the microbiome, evolution, and medicine

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: