Joe Alcock is joined by evolutionary anthropologist Kate Rusk of Inertia TV and Science Happy Hour to talk about a recent JAMA article studying fluids for adults with sepsis. Do we give too much fluids for these patients? The JAMA article suggests we do. There have been two randomized controlled trials, both performed in Africa, and in both trials more patients died when they received IV fluids. In other words, modern critical care protocols that are standard in US and many European hospitals tend to kill patients in the developing world. What is up with that? We discuss the implications for evolution and critical care in this episode.