October 13th. Guest Lecture: Roland Cooper PhD

Roland Cooper PhD of Dominican University has spent the last several summers in Kampala Uganda studying resistance patterns to the malaria parasite Plasmodium falciparum. He will be visiting UNM on October 13th and lecturing on the topic of Evolution of Artemisinin Resistance in Plasmodium falciparum malaria.

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Read his recent article  Lack of Artemisinin resistance in Plasmodium falciparum in Uganda based on parasitological and molecular assays published in August in Antimicrobial Agents and Chemotherapy.

Students: additional useful readings:

  1. Fairhurst Artemisinin Review
  2. Malaria Infection Increases Attractiveness of Humans to Mosquitoes. Lacroix R, Mukabana WR, Gouagna LC, Koella JC (2005) PloS Biol 3(9):e298.
  3. NPR Mosquitoes are more likely to seek out human blood after infection with Plasmodium. Another example of hijacking of host neural machinery?
  4. Ashley NEJM article.
  5. Read Curious Orthodoxy Antibiotic Prescribing

Writing Assignment: Artemisinin is modern drug derived from wormwood, an ancient remedy for malaria. Artemisinin in combination with other drugs is the last effective treatment for Falciparum malaria in many places in Asia, and especially in Africa. If you were in charge of the World Health Organization, what are three things you would recommend to ensure that we can still use artemisinin for malaria in Africa 20 years from now. (You will find useful information in readings 1, 4, and 5). 1 page max.

Make up extra credit (only do this if you have missed a writing assignment, or missed a class because of illness, or previously turned in an assignment late). Some research supports the idea that malaria parasites manipulate their hosts (insect and mammal). Explain the proximate and ultimate reasons for these changes (useful information is in readings 2 and 3). 2/3 page single space max.

UNM community and visitors welcome:

Tuesday, October 13th 2015, 5:30PM; 258 Castetter Hall, guest lecture for the Evolutionary Medicine Class:

Directions – Castetter is #21:

Castetter

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