The role of fluids in sepsis continues to be a subject of some debate. Clearly, most patients with severe life-threatening sepsis benefit from the provision of fluids. The choice of fluids – crystalloid, colloid, blood products – is a matter of continued research. Questions regarding the quantity of fluids for initial resuscitation and how to identify hypovolemia in septic patients generate controversy. Importantly, recent evidence suggests that pediatric patients with sepsis should not be treated the same way as adults. This last point may be particularly true with IV fluids. The following is an excellent review about the value of fluids in sepsis that challenges prevailing dogma.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218999/

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Joe Alcock

Emergency Physician, Educator, Researcher, interested in the microbiome, evolution, and medicine