Tomorrow we will talk about the consequences of potential gene-environment mismatch. It is thought that most of human evolution, and thus selection for human genes has occurred during the Pleistocene, an epoch that lasted from about 1 million years ago and ended 12 thousand years ago. Of course we live in a radically different environment now. Could there be a mismatch between genes shaped by selection in the Pleistocene environment now expressed in our modern environment?

Handout is here:

Mismatch Slides

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Joe Alcock

Emergency Physician, Educator, Researcher, interested in the microbiome, evolution, and medicine